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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZAP70
All Species:
21.52
Human Site:
Y126
Identified Species:
43.03
UniProt:
P43403
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P43403
NP_001070.2
619
69872
Y126
R
D
A
M
V
R
D
Y
V
R
Q
T
W
K
L
Chimpanzee
Pan troglodytes
XP_515637
619
69840
Y126
R
D
A
M
V
R
D
Y
V
R
Q
T
W
K
L
Rhesus Macaque
Macaca mulatta
XP_001101570
619
69877
Y126
R
D
A
M
V
R
D
Y
V
R
Q
T
W
K
L
Dog
Lupus familis
XP_861301
601
68596
Y130
K
E
S
L
I
R
E
Y
V
K
Q
T
W
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P43404
618
70040
Y126
R
D
A
M
V
C
D
Y
V
R
Q
T
W
K
L
Rat
Rattus norvegicus
Q64725
629
71510
Y130
K
E
N
L
I
R
E
Y
V
K
Q
T
W
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515271
507
56102
D82
G
S
V
T
E
M
P
D
A
A
A
H
L
P
F
Chicken
Gallus gallus
Q07494
984
109166
N338
G
R
D
D
V
T
Y
N
I
V
C
K
K
C
R
Frog
Xenopus laevis
Q91736
902
100832
W260
E
T
A
I
T
L
E
W
H
P
P
R
E
T
G
Zebra Danio
Brachydanio rerio
O13146
981
109636
V415
H
T
N
Y
T
F
S
V
E
A
L
N
G
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24145
939
104255
H442
P
V
S
P
H
S
H
H
Q
H
P
H
V
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189062
746
84636
L174
M
E
G
A
L
I
D
L
A
K
S
Q
G
M
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.5
53.6
N.A.
93.5
53.7
N.A.
57.6
22.6
24.2
25.2
N.A.
25.1
N.A.
N.A.
34
Protein Similarity:
100
100
98.3
70.4
N.A.
96.1
70.9
N.A.
62.6
35.5
39.1
37.4
N.A.
40.8
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
46.6
N.A.
93.3
46.6
N.A.
0
6.6
6.6
0
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
0
13.3
26.6
0
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
42
9
0
0
0
0
17
17
9
0
0
0
17
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
9
0
0
9
0
% C
% Asp:
0
34
9
9
0
0
42
9
0
0
0
0
0
0
0
% D
% Glu:
9
25
0
0
9
0
25
0
9
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% F
% Gly:
17
0
9
0
0
0
0
0
0
0
0
0
17
0
9
% G
% His:
9
0
0
0
9
0
9
9
9
9
0
17
0
0
0
% H
% Ile:
0
0
0
9
17
9
0
0
9
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
0
0
25
0
9
9
34
0
% K
% Leu:
0
0
0
17
9
9
0
9
0
0
9
0
9
0
50
% L
% Met:
9
0
0
34
0
9
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
17
0
0
0
0
9
0
0
0
9
0
17
0
% N
% Pro:
9
0
0
9
0
0
9
0
0
9
17
0
0
17
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
50
9
0
0
0
% Q
% Arg:
34
9
0
0
0
42
0
0
0
34
0
9
0
0
9
% R
% Ser:
0
9
17
0
0
9
9
0
0
0
9
0
0
0
9
% S
% Thr:
0
17
0
9
17
9
0
0
0
0
0
50
0
9
0
% T
% Val:
0
9
9
0
42
0
0
9
50
9
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
50
0
0
% W
% Tyr:
0
0
0
9
0
0
9
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _